IMHRS Meeting: Saturday June 19, 2004


Opening of the Secretariat - Friday June 19th, 2004

07:00 - 17:00 Berlin Hilton Hotel

Plenary workshop W2 - alopecia areata

08:00 - 09:20 Chair:
Vera Price, San Francisco, USA
Pia Freyschmidt-Paul, Marburg, Germany
Amos Gilhar, Haifa, Israel
08:00 - 08:14 Regulatory T-cells in autoimmune diseases and their potential role in alopecia areata
Kevin McElwee, Vancouver, Canada
08:14 - 08:28 Searching for susceptibility genes in alopecia areata
Angela Christiano, New York, USA
08:28 - 08:42 Neurotrophins in autoimmune disease: Implications for alopecia areata
Vladimir Botchkarev, Michael Fessing, Boston, USA
08:42 - 08:56 Alopecia areata resistance in IFN-gamma and IL-2 knockout mice
Pia Freyschmidt-Paul, Marburg, Germany
08:56 - 09:10 Treatment of alopecia areata with anti-interferon gamma
Natalya Sharova, Moscow, Russia
09:10 - 09:20 Genetic mapping in alopecia areata
Hans Christian Hennies, Berlin, Germany

Breakfast seiminar B4 - mapping of genetic hair diseases

08:00 - 09:20 Chair:
Jorge Frank, Aachen, Germany
Abraham Zlotogorski, Jerusalem, Israel
08:00 - 08:10 Hypotrichosis simplex of the scalp is caused by nonsense mutations in the crneodesmosin gene
Elon Pras, Tel Hashomer, Israel
08:10 - 08:20 Clincal and pathological correlations in genetically distinct forms of atrichia
Abraham Zlotogorski, Jerusalem, Israel
08:20 - 08:30 Mutation in the desmoglein 4 gene underlie localized autosomal recessive hypotrichosis in humans, rats, and mice
Amalia Martinez-Mir, New York, USA
08:40 - 08:50 A genetic locus for pili annulati
Jack Green, Melbourne, Australia
08:50 - 09:00 A gene locaus responsible for pili annulati maps to chromosome 12Q24.32-24.33
Kathrin Giehl, Munich, Germany
09:00 - 09:10 Genetic analysis of HLA-DR/-DQ/NOTCH4/-B in alopecia areata reveals more than one susceptibility haplotype within the MHC region
Rachid Tazi-Ahnini, Sheffield, UK
09:10 - 09:20 Congenital alopecia and nail dystrophy with severe T-cell immunodeficiency: A unique phenotype of a misdiagnosed entity?
Jorge Frank, Aachen, Germany

Breakfast seiminar B5 - mesenchymal-epithelial interaction

08:00 - 09:20 Chair:
Colin Jahoda, Durham, UK
Seiji Arase, Tokushimo, Japan
08:00 - 08:10 Epithelial-mesenchymal interactions between hair follicle stem cells and dermal papilla cells: A genechip analysis
Cecilia Roh, Houston, USA
08:10 - 08:20 Interactions between the epidermis and dermal pailla in vitro
Alessandro Amici, Chiba, Japan
08:20 - 08:45 Epithelial-mesenchymal regulation of feather follicular stem cells
Chen-Ming Chuong, Los Angeles, USA
08:45 - 09:05 Signalling from dermal papilla cells
Jiro Kishimoto, Yokohama, Japan

Breakfast seiminar B6 - mesenchymal-epithelial interaction

08:00 - 09:20 Chair:
Vladimir Botchkarev, Boston, USA
Ralf Paus, Hamburg, Germany
Eva Peters, Berlin, Germany
08:00 - 08:20 Nerve growth factor regulates the cutaneous inflammatory response to stress and prematurely terminates murine hair growth
Eva Peters, Berlin, Germany
08:20 - 08:40 Nerves, neuropeptides, and the human anagen hair follicle
Maria Hordinsky, Minnesota, USA
08:40 - 09:00 Characteristics and potential functions of the hypothalamus-pituitary-adrenal axis (HPA)-equivalent of the human hair follicle
Ralf Paus, Hamburg, Germany
09:00 - 09:15 Topical application of the neuroimmunophilin ligand analogs induces anagen hair growth in C57BL/6J mice
Marna Ericson, Minneapolis, USA

Plenary session S7 - morphology, structure, and function of the hair shaft

09:30 - 11:00 Chair:
Leslie Jones, Melbourne, Australia
Claude Bouillon, Paris, France
Ryoji Tsuboi, Tokyo, Japan
09:30 - 10:00 Plenary lecture
Ethnic hair
Victoria Holloway, Chicago, USA
10:00 - 10:20

Keratin assoicated proteins
Yutaka Shimomura, Niiagata, Japan

10:20 - 10:40 Keratins - pathfinders in the hair follicle compartment
Lutz Langbein, Heidelberg, Germany
10:40 - 10:55 Integral lipid in human hair follicle
Won-Soo Lee, Kangwon-Do, Korea
11:00 - 11:30 Coffee break
Industrial exhibition
Poster discussions (even numbers)

Plenary session S8 - morphogenesis and hair cycling

11:30 - 13:00 Chair:
Alexander Awgulewitsch, Charleston, USA
Motonobu Nakamura, Kyoto, Japan
11:30 - 12:00

WNT signals are required for the initiation of hair follicle development and for maintenance of postnatal hair growth
Sarah Miller, Philadelphia, USA

12:00 - 12:15

Pathways of hair follicle differentiation involving HOXC13
Alexander Awgulewitsch, Charleston, USA

12:15 - 12:30

Hair cycle-dependent remodelling of the skin vasclature is mediated by changes in the expression of key blood regulators of vessel remodelling and their cognate receptors
Ralf Paus, Hamburg, Germany

12:30 - 12:45 Involvement of EDAR signaling in the control of hair shaft formation and catagen development during the hair cycle
Vladimir Botchkarev, Michael Fessing, Boston, USA
12:45 - 13:00 The morphogenesis of scales in zebrafish: A model for hair/teeth formation
Vu Nguyen, Philadelphia, USA
Lunch break
13:00 - 14:30 Industrial Exhibition
Satelite Symposium
Luncheon Seminars

Plenary workshop W3 - hair diagnostic techniques and practical advice

13:00 - 14:15 Chair:
Jeffrey Miller, Hershey, USA
Rolf Hoffmann, Freiburg, Germany
Douglas Canfield, Fairfield, USA
13:00 - 13:15

The 60 second hair count revisited
Jeffrey Miller, Hershey, USA

13:15 - 13:30

Trichoscan: New data and what comes next
Rolf Hoffmann, Freiburg, Germany

13:30 - 13:45

A rondomized, double-blind, placebo-controlled clinical trial evaluating hair shaft width utilizing new photographic methodology in male patients being treated for androgenetic alopecia with 5% minoxidil topical solution
Douglas Canfield, Fairfield, USA

13:45 - 14:00

Specific signals from anagen to exogen are detected in vivo by non invasive scalp hair cycle monitoring method in male and female patterned or female diffuse hair loss
Dominique Van Neste, Tournai, Belgium

14:00 - 14:15

Alopecia areata investigational assessment guidelines - part II
Elise Olsen, Durham, USA

Luncheon seminar 4 - rare and tropical dermatoses of the scalp and hair

13:00 - 14:15 Chair:
Mohsen Soliman, Cairo, Egypt
Adrian Pierini, Buenos Aires, Argentina
Wen Chieh Chen, Kaohsiung, Taiwan
13:00 - 13:30

Rare and tropical dermatoses of the scalp and hair
Mohsen Solimen, Cairo, Egypt

13:30 - 13:40

Extreme female predominance in adult tinea capitis unveiled by tinea captitis in Southern Taiwan, 1988-2003
Mark Ming-Long Hsu, Tainan, Taiwan

13:40 - 13:50

Microscopic and clinical hair disorders among Egyptians: A postgraduate course
Adel Botros, Zaghloul, Cairo, Egypt

13:50 - 14:00

Nevoid basal cell carcinoma syndrome with multiple hair shaft defects
Razel Lurie, Petah Tivka, Israel

14:00 - 14:15

Alopecia areata associated with pityriasis lichenoides et varioliformis acuta and nevus flammeus
Wen Chieh Chen, Kaohsiung, Taiwan

Luncheon seminar 5 - animal models and hair diseases

13:00 - 14:15 Chair:
John Sundberg, Bar Harbor, USA
Dominique Van Neste, Tournai, Belgium
Kevin McElwee, Vancouver, Canada
13:00 - 13:15

Transfer of CD8+ cells induces localized hair loss while CD4+/CD25- cells promote systemic alopecia areata and CD4+/CD25+ cells partially blockade disease onset in the C3H/HeJ mouse model
Kevin McElwee, Vancouver, Canada

13:15 - 13:30

Mouse models for understanding sebaceous gland differentiation
Rebecca Porter, Dundee, UK

13:30 - 13:45

Expression of cyclooxygenase isozymes during morphogenesis and cycling of pelage hair follicles in mouse skin: Precocious onset of the first catagen phase and alopecia upon cyclooxygenase-2 overexpression
Karin Muller-Decker, Heidelberg, Germany

13:45 - 14:00

Hair cycle specific immunolocalization of retinoic acid synthesis markers
Helen Everts, Nashville, USA

14:00 - 14:15

Bulge region and epidermal basal layer specific expression of fibroblast growth factor - 13 (FHF-2) in mouse skin
Toru Imamura, Tsukuba, Japan

Luncheon seminar 6 - natural products for hair care and treatment

13:00 - 14:15 Chair:
Wilma Bergfeld, Cleveland, USA
Bianca Maria Piraccini, Bologna, Italy
13:00 - 13:15

Nutrients and hair growth, current concepts
Wilma Bergfeld, Cleveland, USA

13:15 - 13:30

Natural hair dyes
John Gray, Staines, UK

13:30 - 13:45

The importance of iron deficiency in patients with hair loss. Iron supplement is helpful!
Wilma Bergeld, Cleveland, USA

13:45 - 14:00

Phytosterols and hair treatment
Bianca Maria Piraccini, Bologna, Italy

Plenary session S9 - follicular targeting and penetration

14:00 - 15:45 Chair:
Hans Schaefer, Berlin, Germany
Kurt Stenn, Philadelphia, USA
Byung In Ro, Seoul, Korea
14:45 - 15:15 Plenary Lecture
Follicular targeting from basic science to clinical implication
George Cotsarelis, Philadelphia, USA
15:15 - 15:30 Follicular targeting: A promising tool in selective dermatotherapy
Annika Vogt, Berlin, Germany
15:30 - 15:45 Role of arylhydrocarbon receptor nuclear translocator (ARNT) in dioxin toxicity and epidermal barrier formation in mouse skin
Andrey Panteleyev, Columbia, USA

Closing ceremony

15:30 - 16:00 Poster awards
Closing remarks

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